Synaesthesia in children

Synaesthesia is a developmental condition that triggers phantom sensations (e.g., colours or tastes) when exposed to everyday stimuli such as graphemes, music, and pain. Yet, despite synaesthesia being a developmental condition, there is very little work in children to date. In this thesis, I explore two types of synaesthesia in children aged 6-10 years old; grapheme-colour synaesthesia (letters and numbers elicit colours) and grapheme-personality synaesthesia (letters and numbers elicit personalities). I first use tests designed specifically for children to identify individuals with these types of synaesthesia. Here I tested children with and without synaesthesia who had been identified from a very large screening endeavour, called MULTISENSE (funded by the European Research Council; I played a central role in this project, but my thesis focuses on the children identified by this process, rather than the screening itself). Then once this cohort was identified I looked at group differences between synaesthetes and non-synaesthetes in two domains: personality and cognition (specifically, numerical cognition). Throughout the thesis I use tests targeted specifically for our child population. Where these did not already exist in Chapter 2 (e.g., suitable self-report personality measures for children) we created and validated them independently. In Chapter 3 I use some of these measures to identify whether synaesthetes have a different personality profile to non-synaesthetes. In the second half of the thesis I tested synaesthetes’ numerical cognition, and looked, too, at ‘synaesthesia-like’ phenomena in the general population. Here in Chapter 4 I explored whether a widely implemented maths tool that pairs numbers with colours aids non-synaesthete children in their numerical cognition. I then finally return to synaesthetes in Chapter 5 using the same tests of numerical cognition to determine if grapheme-colour synaesthetes show advantages in this domain. Overall, this thesis shows that child synaesthetes have a distinct personality profile, and show a pattern of differences in numerical cognition found also in ‘synaesthesia-like’ phenomena such as the educational colour-coding of numbers

Well-being measures for younger children

Understanding variations in children’s well-being is key to addressing inequalities. It is especially useful to understand children’s own perspectives, although there is a lack of short questionnaires using simple language which can be administered to younger children (or in situations when testing-time is limited). Here we first present the VSWQ-C, a Very Short Well-Being Questionnaire for Children, which captures health-related quality-of-life in a brief questionnaire for both older and younger child responders. We provide preliminary validation evidence for this new measure from two English samples of children aged 6–7 and 9–10 years. Next, we also adapted an existing measure of children’s emotional well-being (10-item Positive and Negative Effect Schedule for Children; Ebesutani et al., 2012), again to be suitable for a younger cohort. Our adaptation, the Definitional Positive and Negative Effect Schedule for Children (dPANAS-C), provides children as young as 6 with age-appropriate definitions of questionnaire vocabulary. We again present preliminary validation evidence from 9–10 year olds, as well as children 6–7 years (i.e., 1–2 years younger than the original version of this questionnaire had been psychometrically developed for). We looked too at demographic influences, and show that older children report greater well-being (in the VSWQ-C) as well as lower negative affect (in the dPANAS-C), but without gender differences. Our findings show that our tools eliciting self-reports of well-being are valuable and valid instruments for children as young as 6 years, with acceptable reliability and strong convergent validity

Poorer well-being in children with misophonia: evidence from the Sussex misophonia Scale for adolescents

Objective: Misophonia is an unusually strong aversion to a specific class of sounds – most often human bodily sounds such as chewing, crunching, or breathing. A number of studies have emerged in the last 10 years examining misophonia in adults, but little is known about the impact of the condition in children. Here we set out to investigate the well-being profile of children with misophonia, while also presenting the first validated misophonia questionnaire for children. Materials and Methods: We screened 142 children (10–14 years; Mean 11.72 SD 1.12; 65 female, 77 male) using our novel diagnostic [the Sussex Misophonia Scale for Adolescents (SMS-Adolescent)]. This allowed us to identify a group of children already manifesting misophonia at that age – the first population-sampled cohort of child misophonics examined to date. Children and their parents also completed measures of well-being (for convergent validation of our SMS-Adolescent) and creative self-construct (for discriminant validation). Results: Data show that children with misophonia have significantly elevated levels of anxiety and obsessive compulsive traits. Additionally children with misophonia have significantly poorer life-satisfaction, and health-related quality of life. As predicted, they show no differences in creative self-construct. Conclusion: Together our data suggest the first evidence in population sampling of poorer life outcomes for children with misophonia, and provide preliminary convergent and discriminant validation for our novel misophonia instrument. Our data suggest a need for greater recognition and therapeutic outlets for adolescents with misophonia

Numeracy skills in child synaesthetes: Evidence from grapheme-colour synaesthesia

Grapheme-colour synaesthesia is a neurological trait that causes lifelong colour associations for letter and numbers. Synaesthesia studies have demonstrated differences between synaesthetes and non-synaesthetes in ways that extend beyond synaesthesia itself (e.g., differences in their cognition, personality, and creativity). This research has focused almost exclusively on adult synaesthetes, and little is known about the profiles of synaesthetic children. By and large, findings suggest advantages for synaesthetes (e.g., Chun & Hupé, 2016; Havlik et al., 2015, Rothen et al., 2012; Rouw & Scholte, 2016; Simner & Bain, 2018) although differences in mathematical ability are unclear: some research indicates advantages (e.g., Green & Goswami, 2008) whilst others suggest difficulties (e.g., Rich et al., 2005). In the current study, we tested numerical cognition in a large group of children with grapheme-colour synaesthesia. Synaesthetes with coloured numbers showed advantages over their peers in their sense of numerosity, but not in their curriculum mathematics ability. We discuss how our findings speak to models for synaesthesia, to methodologies for assessing number cognition (e.g., dot numerosity tasks), and to the wider educational practice of using coloured number-tools in schools (e.g., Numicon; Oxford University Press, 2018)

Wellbeing differences in children with synaesthesia: anxiety and mood regulation

Synaesthesia is a neurodevelopmental trait that causes unusual sensory experiences (e.g., perceiving colours when reading letters and numbers). Our paper represents the first evidence that synaesthesia can impact negatively on children’s well-being, and that there are likely to be important mental health co-morbidities for children with synaesthesia. We recruited 76 synaesthetes aged 6-10 years who had one of two types of synaesthesia (grapheme-colour synaesthesia and sequence-personality synaesthesia), and compared them to almost one thousand matched non-synaesthete controls. We tested children’s wellbeing with two different measures, and found a significant relationship between synaesthesia and affect (i.e., mood), and also between synaesthesia and anxiety. Children with synaesthesia showed evidence suggesting significantly higher rates of Anxiety Disorder, and also displayed a type of mood-moderation in demonstrating fewer extremes of emotion (i.e., significantly fewer negative feelings such as fear, but also significantly fewer positive feelings such as joy). We discuss our results with reference to the emotional moderation of alexithymia (the inability to recognize or describe one's own emotions), and to a set of known links between alexithymia, anxiety, autism and synaesthesia

Mental health difficulties in children who develop misophonia: an examination of ADHD, depression & anxiety

Misophonia is a sound sensitivity disorder characterized by unusually strong aversions to a specific class of sounds (e.g., eating sounds). Here we demonstrate the mental health profile in children who develop misophonia, examining depression, anxiety and ADHD. Our participants were members of the birth cohort ALSPAC (Avon Longitudinal Study of Parents and Children). We screened them for misophonia as adults, then analysed their retrospective mental health data from ages 7 to 16 years inclusive, reported from both children and parents. Data from their Development and Wellbeing Assessments (7–15 years) and their Short Mood and Feelings Questionnaires (9–16 years) show that our misophonia group had a greater likelihood of childhood anxiety disorder and depression in childhood (but not ADHD). Our data provide the first evidence from a large general population sample of the types of mental health co-morbidities found in children who develop misophonia.</p

What factors influence children's creative artistic orientation? The novel children's creative orientation test: artistic

Creative orientation is the extent to which different individuals are drawn toward creative activities (e.g., art, music). We know relatively little about child-level creative orientation given certain testing limitations. Adult tools often measure time spent engaged in creative pursuits, but this method is unsuitable for children because their free time is often dictated by parents. To overcome this, we devised an entirely novel measure of creative orientation, the Children's Creative Orientation Test: Artistic (C-COT: Artistic). This short task, suitable for children as young as 6, elicits children's creative urges toward artistic pursuits independently of parental influence and provides quantitative scoring. We applied our measure to over 3000 children aged 6–10 years, where it showed robust reliability, suggesting that creative orientation is a stable trait over time. We show that creative orientation is also influenced by classroom cohort, age, and gender but is unaffected by socio-economic status or seasonal changes (autumn vs. spring testing). We showed too that creative orientation converges with creative thinking (divergent thinking), creative personality (openness to experiences, especially the aesthetics subtrait), and creative engagements in the home. We present our test here in full, as a simple, fast, and robust measure of creative artistic orientation in children

Measurements of the Total and Differential Higgs Boson Production Cross Sections Combining the H??????? and H???ZZ*???4??? Decay Channels at s\sqrt{s}=8??????TeV with the ATLAS Detector

Measurements of the total and differential cross sections of Higgs boson production are performed using 20.3~fb$^{-1}$ of $pp$ collisions produced by the Large Hadron Collider at a center-of-mass energy of $\sqrt{s} = 8$ TeV and recorded by the ATLAS detector. Cross sections are obtained from measured $H \rightarrow \gamma \gamma$ and $H \rightarrow ZZ ^{*}\rightarrow 4\ell$ event yields, which are combined accounting for detector efficiencies, fiducial acceptances and branching fractions. Differential cross sections are reported as a function of Higgs boson transverse momentum, Higgs boson rapidity, number of jets in the event, and transverse momentum of the leading jet. The total production cross section is determined to be $\sigma_{pp \to H} = 33.0 \pm 5.3 \, ({\rm stat}) \pm 1.6 \, ({\rm sys}) \mathrm{pb}$. The measurements are compared to state-of-the-art predictions.Measurements of the total and differential cross sections of Higgs boson production are performed using 20.3  fb-1 of pp collisions produced by the Large Hadron Collider at a center-of-mass energy of s=8  TeV and recorded by the ATLAS detector. Cross sections are obtained from measured H→γγ and H→ZZ*→4ℓ event yields, which are combined accounting for detector efficiencies, fiducial acceptances, and branching fractions. Differential cross sections are reported as a function of Higgs boson transverse momentum, Higgs boson rapidity, number of jets in the event, and transverse momentum of the leading jet. The total production cross section is determined to be σpp→H=33.0±5.3 (stat)±1.6 (syst)  pb. The measurements are compared to state-of-the-art predictions.Measurements of the total and differential cross sections of Higgs boson production are performed using 20.3 fb$^{-1}$ of $pp$ collisions produced by the Large Hadron Collider at a center-of-mass energy of $\sqrt{s} = 8$ TeV and recorded by the ATLAS detector. Cross sections are obtained from measured $H \rightarrow \gamma \gamma$ and $H \rightarrow ZZ ^{*}\rightarrow 4\ell$ event yields, which are combined accounting for detector efficiencies, fiducial acceptances and branching fractions. Differential cross sections are reported as a function of Higgs boson transverse momentum, Higgs boson rapidity, number of jets in the event, and transverse momentum of the leading jet. The total production cross section is determined to be $\sigma_{pp \to H} = 33.0 \pm 5.3 \, ({\rm stat}) \pm 1.6 \, ({\rm sys}) \mathrm{pb}$. The measurements are compared to state-of-the-art predictions

Measurement of the W±ZW^{\pm}Z boson pair-production cross section in pppp collisions at s=13\sqrt{s}=13 TeV with the ATLAS Detector

The production of $W^{\pm}Z$ events in proton--proton collisions at a centre-of-mass energy of 13 TeV is measured with the ATLAS detector at the LHC. The collected data correspond to an integrated luminosity of 3.2 fb$^{-1}$. The $W^{\pm}Z$ candidates are reconstructed using leptonic decays of the gauge bosons into electrons or muons. The measured inclusive cross section in the detector fiducial region for leptonic decay modes is $\sigma_{W^\pm Z \rightarrow \ell^{'} \nu \ell \ell}^{\textrm{fid.}} = 63.2 \pm 3.2$ (stat.) $\pm 2.6$ (sys.) $\pm 1.5$ (lumi.) fb. In comparison, the next-to-leading-order Standard Model prediction is $53.4^{+3.6}_{-2.8}$ fb. The extrapolation of the measurement from the fiducial to the total phase space yields $\sigma_{W^{\pm}Z}^{\textrm{tot.}} = 50.6 \pm 2.6$ (stat.) $\pm 2.0$ (sys.) $\pm 0.9$ (th.) $\pm 1.2$ (lumi.) pb, in agreement with a recent next-to-next-to-leading-order calculation of $48.2^{+1.1}_{-1.0}$ pb. The cross section as a function of jet multiplicity is also measured, together with the charge-dependent $W^+Z$ and $W^-Z$ cross sections and their ratio